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KMID : 0616120100410010058
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Korean Journal of Pharmacognosy
2010 Volume.41 No. 1 p.58 ~ p.61
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Quantitative Analysis of Marker Substance in Fermented Rehmanniae Radix Preparata
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Park Hwa-yong
Um Young-Ran
Ma Jin-Yeul
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Abstract
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Medicinal plant Rehmanniae Radix has long been used as traditional herbal medicine in Korea. In this study, we investigated quantitative changes of marker substance 5-hydroxymethyl-2-furaldehyde (5-HMF) in Rehmanniae Radix
Preparata fermented with Ganoderma lucidum, Paecilomyces japonica, honey, and Nuruk, using HPLC according to the
Korean Pharmacopoeia. As a result, 5-HMF was decreased in SDT and SYT, and increased in SST and SNT, comparing with control group. Quantitative increasing of 5-HMF is not exactly in direct proportion with fermentation, and it is need further studies to elucidate mechanism of quantitative changes by converted and newly produced substances with fermentation.
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KEYWORD
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Rehmanniae Radix Preparata, fermentation, 5-HMF
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